Retrieval analysis of different orthodontic brackets: the applicability of electron microprobe techniques for determining material heterogeneities and corrosive potential

OBJECTIVE: The objective of this study was to investigate the applicability of micro-analytical methods with high spatial resolution to the characterization of the composition and corrosion behavior of two bracket systems. MATERIAL AND METHODS: The surfaces of six nickel-free brackets and six nickel-containing brackets were examined for signs of corrosion and qualitative surface analysis using an electron probe microanalyzer (EPMA), prior to bonding to patient's tooth surfaces and four months after clinical use. The surfaces were characterized qualitatively by secondary electron (SE) images and back scattered electron (BSE) images in both compositional and topographical mode. Qualitative and quantitative wavelength-dispersive analyses were performed for different elements, and by utilizing qualitative analysis the relative concentration of selected elements was mapped two-dimensionally. The absolute concentration of the elements was determined in specially prepared brackets by quantitative analysis using pure element standards for calibration and calculating correction-factors (ZAF). RESULTS: Clear differences were observed between the different bracket types. The nickel-containing stainless steel brackets consist of two separate pieces joined by a brazing alloy. Compositional analysis revealed two different alloy compositions, and reaction zones on both sides of the brazing alloy. The nickel-free bracket was a single piece with only slight variation in element concentration, but had a significantly rougher surface. After clinical use, no corrosive phenomena were detectable with the methods applied. Traces of intraoral wear at the contact areas between the bracket slot and the arch wire were verified. CONCLUSION: Electron probe microanalysis is a valuable tool for the characterization of element distribution and quantitative analysis for corrosion studies

Making Anti-de Sitter Black Holes

It is known from the work of Banados et al. that a space-time with event horizons (much like the Schwarzschild black hole) can be obtained from 2+1 dimensional anti-de Sitter space through a suitable identification of points. We point out that this can be done in 3+1 dimensions as well. In this way we obtain black holes with event horizons that are tori or Riemann surfaces of genus higher than one. They can have either one or two asymptotic regions. Locally, the space-time is isometric to anti-de Sitter space.Comment: LaTeX, 10 pages, 6 postscript figures, uses epsf.te

Schwarz Methods: To Symmetrize or Not to Symmetrize

A preconditioning theory is presented which establishes sufficient conditions for multiplicative and additive Schwarz algorithms to yield self-adjoint positive definite preconditioners. It allows for the analysis and use of nonvariational and nonconvergent linear methods as preconditioners for conjugate gradient methods, and it is applied to domain decomposition and multigrid. It is illustrated why symmetrizing may be a bad idea for linear methods. It is conjectured that enforcing minimal symmetry achieves the best results when combined with conjugate gradient acceleration. Also, it is shown that the absence of symmetry in the linear preconditioner is advantageous when the linear method is accelerated by using the Bi-CGstab method. Numerical examples are presented for two test problems which illustrate the theory and conjectures

STAHL: A Novel Scan-Test-Aware Hardened Latch Design

As modern technology nodes become more susceptible to soft errors, many radiation hardened latch designs have been proposed. However, redundant circuitry used to tolerate soft errors in such hardened latches also reduces the test coverage of cell-internal manufacturing defects. To avoid potential test escapes that lead to soft error vulnerability and reliability issues, this paper proposes a novel Scan-Test-Aware Hardened Latch (STAHL). Simulation results show that STAHL has superior defect coverage compared to previous hardened latches while maintaining full radiation hardening in function mode.24th IEEE European Test Symposium (ETS\u2719), May 27-31, 2019, Baden-Baden, German

Impaired nutrient signaling and body weight control in a Na⁺ neutral amino acid cotransporter (Slc6a19)-deficient mouse

Amino acid uptake in the intestine and kidney is mediated by a variety of amino acid transporters. To understand the role of epithelial neutral amino acid uptake in whole body homeostasis, we analyzed mice lacking the apical broad-spectrum neutral (0) amino acid transporter BᴼAT1 (Slc6a19). A general neutral aminoaciduria was observed similar to human Hartnup disorder which is caused by mutations in SLC6A19. Na⁺ -dependent uptake of neutral amino acids into the intestine and renal brush-border membrane vesicles was abolished. No compensatory increase of peptide transport or other neutral amino acid transporters was detected. Mice lacking BᴼAT1 showed a reduced body weight. When adapted to a standard 20% protein diet, BᴼAT1-deficient mice lost body weight rapidly on diets containing 6 or 40% protein. Secretion of insulin in response to food ingestion after fasting was blunted. In the intestine, amino acid signaling to the mammalian target of rapamycin (mTOR) pathway was reduced, whereas the GCN2/ATF4 stress response pathway was activated, indicating amino acid deprivation in epithelial cells. The results demonstrate that epithelial amino acid uptake is essential for optimal growth and body weight regulation.This work was supported by National Health and Medical Research Council Grant 525415, Australian Research Council Grant DP0877897, University of Sydney Bridging Grant RIMS2009-02579), and by an anonymous foundatio

Black Holes and Wormholes in 2+1 Dimensions

A large variety of spacetimes---including the BTZ black holes---can be obtained by identifying points in 2+1 dimensional anti-de Sitter space by means of a discrete group of isometries. We consider all such spacetimes that can be obtained under a restriction to time symmetric initial data and one asymptotic region only. The resulting spacetimes are non-eternal black holes with collapsing wormhole topologies. Our approach is geometrical, and we discuss in detail: The allowed topologies, the shape of the event horizons, topological censorship and trapped curves.Comment: 23 pages, LaTeX, 11 figure

A Spinning Anti-de Sitter Wormhole

We construct a 2+1 dimensional spacetime of constant curvature whose spatial topology is that of a torus with one asymptotic region attached. It is also a black hole whose event horizon spins with respect to infinity. An observer entering the hole necessarily ends up at a "singularity"; there are no inner horizons. In the construction we take the quotient of 2+1 dimensional anti-de Sitter space by a discrete group Gamma. A key part of the analysis proceeds by studying the action of Gamma on the boundary of the spacetime.Comment: Latex, 28 pages, 7 postscript figures included in text, a Latex file without figures can be found at http://vanosf.physto.se/~stefan/spinning.html Replaced with journal version, minor change

Urban Atmospheric Boundary-Layer Structure in Complex Topography: An Empirical 3D Case Study for Stuttgart, Germany

Investigation of the atmospheric boundary-layer structure in urban areas can be challenged by landscape complexity and the heterogenous conditions this instills. Stuttgart, Germany, is a city situated in a bowl-shaped basin and troubled by the accumulation of pollutants during weak-wind conditions. The center of Stuttgart is surrounded by steep slopes up to 250m above the basin floor, except for an opening to the northeast that allows runoff towards the Neckar river. Urban planning and regulation of air quality require advanced monitoring and forecasting skills, which in turn require knowledge about the structure of the atmospheric boundary layer (ABL), down to the surface. Three dimensional observations of the ABL were collected in the City Centre of Stuttgart in 2017. A laser ceilometer and a concerted network of Doppler lidar systems were deployed on roof-tops, providing continuous observations of the cloud base, the mixing-layer height and the three-dimensional wind field. The impact of weak-wind conditions, the presence of shear layers, properties of convective cells and the impact of nocturnal low-levels jets were studied for representative days in winter and summer. The observations revealed the development of distinctive layers with high directional deviation from the flow aloft, reoccurring as a dominant diurnal pattern. Our findings highlight the influence of topography and surface heterogeneity on the structure of the ABL and development of flow regimes near the surface that are relevant for the transport of heat and pollutants